RASD1 anticorps (AA 1-281)

N° du produit ABIN7869043

Cet anticorps anti-RASD1 Polyclonal Lapin (ABIN7869043) détecte spécifiquement RASD1 dans WB, ELISA et FACS. L’anticorps est réactif avec des échantillons de Souris, Humain et Rat.

Aperçu rapide pour RASD1 anticorps (AA 1-281) (ABIN7869043)

Antigène: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Reactivité: Souris, Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-RASD1 anticorps

Épitope: AA 1-281

Fonction: Dexras1 Antibody / RASD1

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids M1-S281) was used as the immunogen for the Dexras1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Dexras1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Dexras1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur RASD1

Antigène: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Autre désignation: Dexras1

Sujet: Dexamethasone-induced Ras-related protein 1 (RASD1) is a protein that in humans is encoded by the RASD1 gene on chromosome 17. This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9Y272