FOXD1 anticorps (AA 1-30)

N° du produit ABIN7869089

Cet anticorps Lapin Polyclonal détecte spécifiquement FOXD1 dans WB, IHC (p) et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour FOXD1 anticorps (AA 1-30) (ABIN7869089)

Antigène: FOXD1 (Forkhead Box D1 (FOXD1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-FOXD1 anticorps

Épitope: AA 1-30

Fonction: FOXD1 Antibody / Forkhead box protein D1

Purification: Antigen affinity

Immunogène: A portion of amino acids 1-30 from the human protein was used as the immunogen for the FOXD1 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the FOXD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the FOXD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur FOXD1

Antigène: FOXD1 (Forkhead Box D1 (FOXD1))

Autre désignation: FOXD1

Sujet: FOXD1 belongs to the forkhead box protein family, specifically the forkhead box D (FOX D) subfamily. It is involved in regulating gene expression by binding to specific DNA sequences and influencing transcription. FOXD1 is known to play essential roles in embryonic development, particularly in the formation of various tissues and organs. In addition, it has been implicated in the regulation of cell proliferation, differentiation, and survival. It is also involved in the development of the kidney and nervous system. Studies have shown that FOXD1 is essential for the formation of the metanephric mesenchyme, a precursor structure for the kidney. Moreover, FOXD1 has been linked to neurogenesis and neuronal differentiation, highlighting its crucial role in brain development. Dysregulation of FOXD1 expression has been associated with several diseases and disorders. For instance, aberrant expression of FOXD1 has been observed in various cancers, including breast cancer, lung cancer, and renal cell carcinoma. In these contexts, FOXD1 may act as an oncogene or tumor suppressor, depending on the cellular context and signaling pathways involved. Furthermore, FOXD1 has been implicated in the pathogenesis of neurodevelopmental disorders, such as autism and schizophrenia. Studies have suggested that dysregulated FOXD1 expression may contribute to the atypical brain development seen in these conditions.

UniProt: Q16676