HDAC11 anticorps (AA 1-30)
Aperçu rapide pour HDAC11 anticorps (AA 1-30) (ABIN7869091)
Antigène
Voir toutes HDAC11 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-30
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Fonction
- HDAC11 Antibody
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Purification
- Purified
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Immunogène
- A portion of amino acids 1-30 from the human protein was used as the immunogen for the HDAC11 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the HDAC11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the HDAC11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- HDAC11 (Histone Deacetylase 11 (HDAC11))
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Autre désignation
- HDAC11
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Sujet
- HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.
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UniProt
- Q96DB2
Antigène
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