Cet anticorps anti-HDAC11 Polyclonal Lapin (ABIN7869091) détecte spécifiquement HDAC11 dans WB et IHC (p).
L’anticorps est réactif avec des échantillons de Humain et Souris.
The stated application concentrations are suggested starting points. Titration of the HDAC11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the HDAC11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Antigène
HDAC11
(Histone Deacetylase 11 (HDAC11))
Autre désignation
HDAC11
Sujet
HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.