GATA4 anticorps (AA 1-332)

N° du produit ABIN7869201

L’anticorps anti-GATA4 Polyclonal Lapin est utilisé pour la détection de GATA4 dans des échantillons de Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour GATA4 anticorps (AA 1-332) (ABIN7869201)

Antigène: GATA4 (GATA Binding Protein 4 (GATA4))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GATA4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GATA4 anticorps

Épitope: AA 1-332

Fonction: Zebrafish Gata4 Antibody / GATA-binding factor 4

Purification: Antigen affinity chromatography

Immunogène: E. coli-derived zebrafish Gata4 recombinant protein (amino acids M1-M332) was used as the immunogen for the Zebrafish Gata4 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish Gata4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish Gata4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur GATA4

Antigène: GATA4 (GATA Binding Protein 4 (GATA4))

Autre désignation: Gata4

Sujet: GATA-binding factor 4 (Gata4) is a zinc finger transcription factor belonging to the GATA family, which regulates gene expression during embryonic development and cell differentiation. In zebrafish (Danio rerio), Gata4 plays a critical role in the development of the heart, endoderm, and gastrointestinal tract, mirroring its conserved function in vertebrate organogenesis.

Gata4 is expressed early during zebrafish embryogenesis, particularly in the cardiac mesoderm and endodermal precursors. It functions as a key regulator of cardiomyocyte differentiation, heart tube formation, and gut development. Gata4 also interacts with other transcription factors such as Nkx2.5 and Tbx5 to coordinate cardiac gene expression programs.

Due to its essential role in heart development and its evolutionary conservation, zebrafish Gata4 is widely studied in models of congenital heart disease, organ specification, and regenerative biology. It serves as a valuable molecular marker and research target for developmental biology, gene regulation, and disease modeling.

UniProt: Q09JY7

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis