HSD17B8 anticorps (AA 1-336)

N° du produit ABIN7869210

L’anticorps anti-HSD17B8 Polyclonal Lapin est utilisé pour la détection de HSD17B8 dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC (p).

Aperçu rapide pour HSD17B8 anticorps (AA 1-336) (ABIN7869210)

Antigène: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD17B8 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HSD17B8 anticorps

Épitope: AA 1-336

Fonction: RING2 Antibody / RNF2 / RING1B

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids M1-K336) was used as the immunogen for the RING2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the RING2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the RING2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur HSD17B8

Antigène: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Autre désignation: RING2

Sujet: E3 ubiquitin-protein ligase RING2 is an enzyme that in humans is encoded by the RNF2 gene. Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

UniProt: Q99496

Pathways: Steroid Hormone Biosynthesis