PHYHIPL anticorps (AA 1-336)

N° du produit ABIN7869211

Cet anticorps anti-PHYHIPL Polyclonal Lapin (ABIN7869211) détecte spécifiquement PHYHIPL dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PHYHIPL anticorps (AA 1-336) (ABIN7869211)

Antigène: PHYHIPL (Phytanoyl-CoA 2-Hydroxylase Interacting Protein-Like (PHYHIPL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHYHIPL est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PHYHIPL anticorps

Épitope: AA 1-336

Fonction: PHYHIPL Antibody / Phytanoyl-CoA hydroxylase-interacting protein-like

Purification: Immunogen affinity purified

Immunogène: E.coli-derived human PHYHIPL recombinant protein (Position: M1-D336) was used as the immunogen for the PHYHIPL antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PHYHIPL antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PHYHIPL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PHYHIPL

Antigène: PHYHIPL (Phytanoyl-CoA 2-Hydroxylase Interacting Protein-Like (PHYHIPL))

Autre désignation: PHYHIPL

Sujet: PHYHIPL antibody detects Phytanoyl-CoA hydroxylase-interacting protein-like, a poorly characterized cytoplasmic protein implicated in neuronal signaling and lipid metabolism. Although its precise biochemical function remains under investigation, PHYHIPL is thought to participate in protein-protein interactions related to peroxisomal fatty acid metabolism and neurodevelopmental regulation. The PHYHIPL antibody is used in neuroscience and metabolic studies to explore neuronal protein networks and lipid homeostasis.

PHYHIPL is encoded by the PHYHIPL gene located on human chromosome 10p12.2. The protein is approximately 148 amino acids long and shows sequence similarity to PHYHIP, which interacts with phytanoyl-CoA hydroxylase, an enzyme involved in alpha-oxidation of branched-chain fatty acids. PHYHIPL is expressed in the brain, liver, and heart, suggesting a broader metabolic role than its paralog.

The PHYHIPL antibody detects a 16 kilodalton protein by western blot and displays diffuse cytoplasmic staining under immunofluorescence microscopy. Although the functional data are limited, PHYHIPL has been linked to neuronal differentiation, axonal growth, and synaptic organization through proteomic analyses. It may serve as an adaptor or scaffolding molecule connecting lipid metabolism enzymes with cytoskeletal or signaling components.

Transcriptomic studies reveal that PHYHIPL expression is enriched in developing neural tissues and reduced in neurodegenerative diseases, indicating potential roles in brain maturation and protection. It has also been identified as a candidate biomarker in studies of metabolic syndromes and cardiovascular disease due to altered expression in lipid-related pathways.

Because PHYHIPL likely integrates metabolic and neuronal processes, it serves as a promising research target for understanding how lipid metabolism supports neural function. NSJ Bioreagents provides a validated PHYHIPL antibody optimized for its applications, supporting research into lipid regulation, brain development, and cellular metabolism.

UniProt: Q96FC7