Cet anticorps anti-PCDHB14 Polyclonal Lapin (ABIN7869265) détecte spécifiquement PCDHB14 dans WB, FACS, ELISA et IHC (p).
L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.
PCDHB14
Reactivité: Humain
IF (cc), IF (p)
Hôte: Lapin
Polyclonal
Cy5
Indications d'application
Optimal dilution of the PCDHB14 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
4 °C,-20 °C
Stockage commentaire
After reconstitution, the PCDHB14 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Antigène
PCDHB14
(Protocadherin beta 14 (PCDHB14))
Autre désignation
PCDHB14
Sujet
Protocadherin beta-14 is a protein that in humans is encoded by the PCDHB14 gene. This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.