SNX6 anticorps (AA 1-406)

N° du produit ABIN7869323

Cet anticorps Lapin Polyclonal détecte spécifiquement SNX6 dans WB, ELISA, IF, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SNX6 anticorps (AA 1-406) (ABIN7869323)

Antigène: SNX6 (Sorting Nexin 6 (SNX6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-SNX6 anticorps

Épitope: AA 1-406

Fonction: SNX6 Antibody / Sorting Nexin 6

Purification: Antigen affinity purified

Immunogène: Amino acids M1-T406 from the human protein were used as the immunogen for the SNX6 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the SNX6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the SNX6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SNX6

Antigène: SNX6 (Sorting Nexin 6 (SNX6))

Autre désignation: SNX6

Sujet: SNX6 (Sorting Nexin 6) is a member of the sorting nexin family, a group of proteins that regulate intracellular trafficking and endosomal sorting. It contains a Phox (PX) domain that binds phosphoinositides, allowing SNX6 to associate with membranes of the endosomal system. Through its involvement in vesicular transport, SNX6 helps direct cargo proteins to specific cellular destinations. A SNX6 antibody is widely used in studies of endosomal trafficking, protein sorting, and membrane dynamics.

SNX6 is a component of the retromer complex, which mediates the retrograde transport of proteins from endosomes back to the trans-Golgi network. This pathway is crucial for maintaining receptor recycling, lysosomal enzyme trafficking, and signaling receptor turnover. By studying SNX6 with a SNX6 antibody, researchers can evaluate its role in cargo recognition and retromer function, as well as its contribution to cellular homeostasis.

Beyond vesicle trafficking, SNX6 has been implicated in multiple signaling pathways. It interacts with transforming growth factor beta (TGF-i²) receptors and may influence TGF-i² signaling, thereby linking endosomal sorting to cell growth and differentiation. Dysregulation of SNX6 expression or function has been associated with cancer progression, neurodegeneration, and viral infection. Employing a SNX6 antibody enables scientists to explore these diverse biological roles and to better understand how endosomal dynamics intersect with signaling networks.

NSJ Bioreagents offers a high-quality SNX6 antibody validated for applications including western blot, immunohistochemistry, and immunofluorescence. Choosing a SNX6 antibody from NSJ Bioreagents ensures reliable performance and reproducible results in studies of protein trafficking, retromer biology, and disease-related signaling.

UniProt: Q9UNH7

Pathways: EGFR Signaling Pathway