GFI1 anticorps (AA 1-422)

N° du produit ABIN7869342

L’anticorps anti-GFI1 Polyclonal Lapin est utilisé pour la détection de GFI1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, ELISA, IHC (p) et FACS.

Aperçu rapide pour GFI1 anticorps (AA 1-422) (ABIN7869342)

Antigène: GFI1 (Growth Factor Independent 1 (GFI1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFI1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-GFI1 anticorps

Épitope: AA 1-422

Fonction: GFI1 Antibody

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids M1-K422) was used as the immunogen for the GFI1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the GFI1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the GFI1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur GFI1

Antigène: GFI1 (Growth Factor Independent 1 (GFI1))

Autre désignation: GFI1

Sujet: Zinc finger protein Gfi-1 is a transcriptional repressor that in humans is encoded by the GFI1 gene. It is mapped to 1p22.1. This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.

UniProt: Q99684