IKZF3 anticorps (AA 1-456)

N° du produit ABIN7869384

L’anticorps anti-IKZF3 Polyclonal Lapin est utilisé pour la détection de IKZF3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IF, FACS et IHC (p).

Aperçu rapide pour IKZF3 anticorps (AA 1-456) (ABIN7869384)

Antigène: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IKZF3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-IKZF3 anticorps

Épitope: AA 1-456

Fonction: Aiolos Antibody / IKZF3

Purification: Antigen affinity purified

Immunogène: An E.coli-derived human recombinant protein (amino acids M1-H456) was used as the immunogen for the Aiolos antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Aiolos antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Aiolos antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur IKZF3

Antigène: IKZF3 (IKAROS Family Zinc Finger 3 (Aiolos) (IKZF3))

Autre désignation: Aiolos

Sujet: Zinc finger protein Aiolos also known as Ikaros family zinc finger protein 3 is a protein that in humans is encoded by the IKZF3 gene. This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.

UniProt: Q9UKT9