APEX2 anticorps (AA 1-500)

N° du produit ABIN7869427

Cet anticorps anti-APEX2 Polyclonal Lapin (ABIN7869427) détecte spécifiquement APEX2 dans WB, ELISA et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour APEX2 anticorps (AA 1-500) (ABIN7869427)

Antigène: APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APEX2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-APEX2 anticorps

Épitope: AA 1-500

Fonction: APEX2 Antibody

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids M1-G500) was used as the immunogen for the APEX2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the APEX2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the APEX2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur APEX2

Antigène: APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))

Autre désignation: APEX2

Sujet: APEX2, also called apurinic/apyrimidinic endonuclease like-2, is a member of the apurinic/apyrimidinic (AP) family of endonucleases that initiate the repair of AP sites formed by spontaneous hydrolysis of the N-glycosylic bond, mutagen-induced base release, or damaged-base excision by a DNA repair glycosylase. RT-PCR detected APEX2 expression in HeLa cells, Jurkat cells, and human kidney, brain and fetal brain tissue. The APEX2 gene is mapped to chromosome Xp11.21. APEX2 participates in both nuclear and mitochondrial base excision repair (BER) and it can play a role in processing 3-prime-damaged termini or 3-prime-mismatched nucleotides. Additionally, APEX2 displayed weaker AP site-specific and 3-prime nuclease activities compared to APEX1.

UniProt: Q9UBZ4