KLC1 anticorps (Light Chain)

N° du produit ABIN7869459

L’anticorps anti-KLC1 Monoclonal Souris est utilisé pour la détection de KLC1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB.

Aperçu rapide pour KLC1 anticorps (Light Chain) (ABIN7869459)

Antigène: KLC1 (Kinesin Light Chain 1 (KLC1))

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KLC1 est non-conjugé

Application: Western Blotting (WB)

Clone: 4F2D7

Détail du produit anti-KLC1 anticorps

Épitope: AA 1-537, Light Chain

Fonction: Kinesin light chain 1 Antibody / KLC1

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids M1-D537) was used as the immunogen for the Kinesin light chain 1 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the KLC1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the KLC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur KLC1

Antigène: KLC1 (Kinesin Light Chain 1 (KLC1))

Autre désignation: Kinesin light chain 1

Sujet: Kinesin light chain 1 is a protein that in humans is encoded by the KLC1 gene. Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named kinesin 2, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos, however, the full-length nature and/or biological validity of most of these variants have not been determined.

UniProt: Q07866

Pathways: Ribonucleoprotein Complex Subunit Organization