NBR1 anticorps (AA 1-665)

N° du produit ABIN7869519

L’anticorps anti-NBR1 Polyclonal Lapin est utilisé pour la détection de NBR1 dans des échantillons de Humain et Singe. Il a été validé pour WB, ELISA, IF et FACS.

Aperçu rapide pour NBR1 anticorps (AA 1-665) (ABIN7869519)

Antigène: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NBR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-NBR1 anticorps

Épitope: AA 1-665

Fonction: NBR1 Antibody / Neighbor of BRCA1 gene 1 protein

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids M1-H665) was used as the immunogen for the NBR1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the NBR1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the NBR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur NBR1

Antigène: NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))

Autre désignation: NBR1

Sujet: Neighbor of BRCA1 gene 1 protein is a protein that in humans is encoded by the NBR1 gene. The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.

UniProt: Q14596

Pathways: Autophagy