OCRL anticorps (AA 1-901)

N° du produit ABIN7869609

L’anticorps anti-OCRL Polyclonal Lapin est utilisé pour la détection de OCRL dans des échantillons de Humain. Il a été validé pour WB, ELISA, IHC (p) et IF.

Aperçu rapide pour OCRL anticorps (AA 1-901) (ABIN7869609)

Antigène: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OCRL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-OCRL anticorps

Épitope: AA 1-901

Fonction: OCRL-1 Antibody

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids M1-D901) was used as the immunogen for the OCRL-1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the OCRL-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the OCRL-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur OCRL

Antigène: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Autre désignation: OCRL-1

Sujet: Inositol polyphosphate 5-phosphatase OCRL-1, also known as Lowe oculocerebrorenal syndrome protein, is an enzyme encoded by the OCRL gene located on the X chromosome in humans. This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.

UniProt: Q01968

Pathways: Inositol Metabolic Process