POLR2A/RPB1 anticorps (AA 10-321)

N° du produit ABIN7869698

Cet anticorps Lapin Polyclonal détecte spécifiquement POLR2A/RPB1 dans WB, IF, ELISA, FACS et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris, Rat et Singe.

Aperçu rapide pour POLR2A/RPB1 anticorps (AA 10-321) (ABIN7869698)

Antigène: POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLR2A/RPB1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-POLR2A/RPB1 anticorps

Épitope: AA 10-321

Fonction: POLR2A Antibody / RNA polymerase II subunit RPB1

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids D10-E321) was used as the immunogen for the POLR2A antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the POLR2A antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the POLR2A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur POLR2A/RPB1

Antigène: POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))

Autre désignation: POLR2A

Sujet: DNA-directed RNA polymerase II subunit RPB1, also known as RPB1, is an enzyme that in humans is encoded by the POLR2A gene. It is mapped to 17p13.1. This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

UniProt: P24928

Pathways: Regulatory RNA Pathways