MT-ND3
Reactivité: Humain
WB, ELISA, FACS
Hôte: Lapin
Polyclonal
HRP
Indications d'application
The stated application concentrations are suggested starting amounts. Titration of the MT-ND3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Store at 4oC for up to one month. For long term, aliquot the MT-ND3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
MT-ND3 is a critical subunit of complex I, acting as a catalyst in the transfer of electrons from NADH to ubiquinone. This process is essential for generating the proton gradient necessary for ATP production. Without MT-ND3, the electron transport chain would not be able to function properly, leading to a decrease in ATP production and ultimately, cellular dysfunction. Research has shown that mutations in the gene encoding MT-ND3 can lead to mitochondrial diseases and a range of health problems, including muscle weakness, neurological disorders, and even premature aging.