MT-ND3 anticorps (AA 10-38)
Aperçu rapide pour MT-ND3 anticorps (AA 10-38) (ABIN7869699)
Antigène
Voir toutes MT-ND3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 10-38
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Fonction
- MT-ND3 Antibody / NADH-ubiquinone oxidoreductase chain 3
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Purification
- Antigen affinity
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Immunogène
- A portion of amino acids 10-38 from the human protein was used as the immunogen for this MT-ND3 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the MT-ND3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4oC for up to one month. For long term, aliquot the MT-ND3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MT-ND3 (Mitochondrially Encoded NADH Dehydrogenase 3 (MT-ND3))
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Autre désignation
- MT-ND3
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Sujet
- MT-ND3 is a critical subunit of complex I, acting as a catalyst in the transfer of electrons from NADH to ubiquinone. This process is essential for generating the proton gradient necessary for ATP production. Without MT-ND3, the electron transport chain would not be able to function properly, leading to a decrease in ATP production and ultimately, cellular dysfunction. Research has shown that mutations in the gene encoding MT-ND3 can lead to mitochondrial diseases and a range of health problems, including muscle weakness, neurological disorders, and even premature aging.
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UniProt
- P03897
Antigène
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