TFPI2 anticorps (AA 100-235)
Aperçu rapide pour TFPI2 anticorps (AA 100-235) (ABIN7869766)
Antigène
Voir toutes TFPI2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
-
-
Épitope
- AA 100-235
-
Fonction
- Tissue factor pathway inhibitor 2 Antibody / TFPI2 (azide and preservative free)
-
Purification
- Protein G affinity
-
Immunogène
- A portion of amino acids 100-235 from human TFPI2 protein was used as the immunogen for the Tissue factor pathway inhibitor 2 antibody.
-
Isotype
- IgG1, kappa
-
-
-
-
Indications d'application
- Optimal dilution of the Tissue factor pathway inhibitor 2 antibody should be determined by the researcher.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
Agent conservateur
- Azide free
-
Stock
- -20 °C
-
Stockage commentaire
- Aliquot the Tissue factor pathway inhibitor 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))
-
Autre désignation
- Tissue factor pathway inhibitor 2
-
Sujet
- The extrinsic pathway of blood coagulation is initiated by contact of plasma factor VII with tissue factor, a cellular membrane glycoprotein that normally is segregated from the bloodstream but can be exposed after tissue injury or newly synthesized in endothelial cells or leukocytes after stimulation by endotoxin and cytokines. Inhibition of Factor VIIa tissue factor activity requires a plasma component (tissue factor pathway inhibitor (TFPI), lipoprotein-associated coagulation inhibitor (LACI) or extrinsic pathway inhibitor (EPI)) and factor Xa. TFPI directly inhibits factor Xa, and, in an Xa-dependent fashion, also inhibits the Factor VIIa tissue factor catalytic complex. TFPI is a multivalent, Kunitz-type proteinase inhibitor that circulates in association with plasma lipoproteins VLDL, LDL, and HDL. TFPI-2 (also known as placental protein 5) is a related glycoprotein that was originally isolated from human placenta.
-
UniProt
- P48307
Antigène
-