TFPI2 anticorps (AA 100-235)

N° du produit ABIN7869769

Cet anticorps anti-TFPI2 Monoclonal Souris (Clone TFPI2-13025) (ABIN7869769) détecte spécifiquement TFPI2 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TFPI2 anticorps (AA 100-235) (ABIN7869769)

Antigène: TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TFPI2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TFPI2-13025

Détail du produit anti-TFPI2 anticorps

Épitope: AA 100-235

Fonction: TFPI2 Antibody / Tissue factor pathway inhibitor 2

Purification: Protein G affinity

Immunogène: A portion of amino acids 100-235 from human Tissue factor pathway inhibitor 2 protein was used as the immunogen for the TFPI2 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the TFPI2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the TFPI2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur TFPI2

Antigène: TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))

Autre désignation: TFPI2

Sujet: The extrinsic pathway of blood coagulation is initiated by contact of plasma factor VII with tissue factor, a cellular membrane glycoprotein that normally is segregated from the bloodstream but can be exposed after tissue injury or newly synthesized in endothelial cells or leukocytes after stimulation by endotoxin and cytokines. Inhibition of Factor VIIa tissue factor activity requires a plasma component (tissue factor pathway inhibitor (TFPI), lipoprotein-associated coagulation inhibitor (LACI) or extrinsic pathway inhibitor (EPI)) and factor Xa. TFPI directly inhibits factor Xa, and, in an Xa-dependent fashion, also inhibits the Factor VIIa tissue factor catalytic complex. TFPI is a multivalent, Kunitz-type proteinase inhibitor that circulates in association with plasma lipoproteins VLDL, LDL, and HDL. TFPI-2 (also known as placental protein 5) is a related glycoprotein that was originally isolated from human placenta.

UniProt: P48307