SULT1E1 anticorps (AA 100-294)

N° du produit ABIN7869811

Cet anticorps anti-SULT1E1 Monoclonal Souris (Clone SULT1E1-7124) (ABIN7869811) détecte spécifiquement SULT1E1 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SULT1E1 anticorps (AA 100-294) (ABIN7869811)

Antigène: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SULT1E1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SULT1E1-7124

Détail du produit anti-SULT1E1 anticorps

Épitope: AA 100-294

Fonction: Estrogen Sulfotransferase Antibody / SULT1E1

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 100-294) from the human protein was used as the immunogen for the Estrogen Sulfotransferase antibody.

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal dilution of the Estrogen Sulfotransferase antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Estrogen Sulfotransferase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur SULT1E1

Antigène: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Autre désignation: Estrogen Sulfotransferase

Sujet: The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.

UniProt: P49888

Pathways: Steroid Hormone Biosynthesis