MUC13 anticorps (AA 100-300)

N° du produit ABIN7869849

L’anticorps anti-MUC13 Monoclonal Souris est utilisé pour la détection de MUC13 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour MUC13 anticorps (AA 100-300) (ABIN7869849)

Antigène: MUC13 (Mucin 13, Cell Surface Associated (MUC13))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC13 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MUC13-13111

Détail du produit anti-MUC13 anticorps

Épitope: AA 100-300

Fonction: MUC13 Antibody / Mucin 13

Purification: Protein G affinity

Immunogène: A portion of amino acids 100-300 from human Mucin 13 protein was used as the immunogen for the MUC13 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the MUC13 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the MUC13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur MUC13

Antigène: MUC13 (Mucin 13, Cell Surface Associated (MUC13))

Autre désignation: MUC13

Sujet: Mucins are epithelial glycoproteins with a high content of clustered oligosaccharides that are O-glycoside linked to tandem repeat peptides rich in threonine, serine and proline. Mucin 13 (MUC13), also designated downregulated in colon cancer 1 (DRCC1), is an epithelial and hemopoietic type I membrane protein that undergoes secretion and influences gastrointestinal mucosa levels. It is most abundant in epithelial tissues of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach. Mucin 13 is a good differentiation marker for gastrointestinal mucosa and may also indicate certain gastric tumors. It localizes to the apical membrane of both columnar and goblet cells in the gastrointestinal tract, and within goblet cell thecae. Mucin 13 is a cleaved protein, and the b subunit, containing the cytoplasmic tail, can homodimerize.

UniProt: Q9H3R2