HDAC5 anticorps (AA 102-197)

N° du produit ABIN7869910

Cet anticorps anti-HDAC5 Polyclonal Lapin (ABIN7869910) détecte spécifiquement HDAC5 dans WB, ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour HDAC5 anticorps (AA 102-197) (ABIN7869910)

Antigène: HDAC5 (Histone Deacetylase 5 (HDAC5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HDAC5 anticorps

Épitope: AA 102-197

Fonction: HDAC5 Antibody

Purification: Antigen affinity purified

Immunogène: Amino acids H102-E197 from the human protein were used as the immunogen for the HDAC5 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the HDAC5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the HDAC5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur HDAC5

Antigène: HDAC5 (Histone Deacetylase 5 (HDAC5))

Autre désignation: HDAC5

Sujet: Histone deacetylase 5, also called HDAC5 or KIAA0600, is an enzyme that in humans is encodes by the HDAC5 gene. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. This gene is mapped to 17q21.31. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer.

UniProt: Q9UQL6

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process