FOXL1 anticorps (AA 104-258)

N° du produit ABIN7869966

L’anticorps anti-FOXL1 Monoclonal Souris est utilisé pour la détection de FOXL1 dans des échantillons de Humain. Il a été validé pour WB, IHC (p), IF et FACS.

Aperçu rapide pour FOXL1 anticorps (AA 104-258) (ABIN7869966)

Antigène: FOXL1 (Forkhead Box L1 (FOXL1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FOXL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Clone: PCRP-FOXL1-1F8

Détail du produit anti-FOXL1 anticorps

Épitope: AA 104-258

Fonction: FOXL1 Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 104-258 was used as the immunogen for the FOXL1 antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the FOXL1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the FOXL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur FOXL1

Antigène: FOXL1 (Forkhead Box L1 (FOXL1))

Autre désignation: FOXL1

Sujet: FOXL1 is a 337 amino acid protein encoded by the mouse gene FOXL1. FOXL1 belongs to the forkhead family and contains one forkhead DNA-binding domain. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. forkhead factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1-deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyers patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the Adenomatous Polyposis Coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.

UniProt: Q12951