EDC4 anticorps (AA 1082-1388)
Aperçu rapide pour EDC4 anticorps (AA 1082-1388) (ABIN7870039)
Antigène
Voir toutes EDC4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1082-1388
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Fonction
- EDC4 Antibody / Enhancer of mRNA-decapping protein 4
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Purification
- Affinity purified
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Immunogène
- An E. coli-derived human protein (amino acids K1082-L1388) was used as the immunogen for the EDC4 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the EDC4 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the EDC4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- EDC4 (Enhancer of mRNA Decapping 4 (EDC4))
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Autre désignation
- EDC4
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Sujet
- Enhancer of mRNA-decapping protein 4 is a protein that in humans is encoded by the EDC4 gene. Enhancer of mRNA decapping 4 (EDC4) was originally identified as the autoantigen Ge-1 from a Sjogren's syndrome patient later diagnosed with primary biliary cirrhosis. EDC4 (also known as HEDLS) was later identified as an essential component of cytoplasmic P-bodies responsible for mRNA decapping and degradation. Identified EDC4 protein is found as a pair of isoforms generated by alternative splicing and contains several WD domains and a putative nuclear localization signal. EDC4 co-localizes with other P-body decapping proteins such as DCP1A, DCP2 and GW182. Experimental evidence suggests that EDC4 may be involved in miRNA-mediated translation repression.
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UniProt
- Q6P2E9
Antigène
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