TXNDC5 anticorps (AA 109-403)
Aperçu rapide pour TXNDC5 anticorps (AA 109-403) (ABIN7870056)
Antigène
Voir toutes TXNDC5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 109-403
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Fonction
- TXNDC5 Antibody / Thioredoxin domain-containing protein 5
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Purification
- Antigen affinity purified
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Immunogène
- E. coli-derived recombinant human protein (amino acids M109-R403) was used as the immunogen for the TXNDC5 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the TXNDC5 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the TXNDC5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))
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Autre désignation
- TXNDC5
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Sujet
- Thioredoxin domain-containing protein 5 is a protein that in humans is encoded by the TXNDC5 gene. This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.
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UniProt
- Q8NBS9
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Pathways
- Cell RedoxHomeostasis
Antigène
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