RAP1GAP anticorps (AA 11-661)

N° du produit ABIN7870090

Cet anticorps anti-RAP1GAP Polyclonal Lapin (ABIN7870090) détecte spécifiquement RAP1GAP dans WB, ELISA, IF, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RAP1GAP anticorps (AA 11-661) (ABIN7870090)

Antigène: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAP1GAP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-RAP1GAP anticorps

Épitope: AA 11-661

Fonction: RAP1GAP Antibody / Rap1 GTPase-activating protein 1

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids D11-L661) was used as the immunogen for the RAP1GAP antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the RAP1GAP antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the RAP1GAP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur RAP1GAP

Antigène: RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))

Autre désignation: RAP1GAP

Sujet: Rap1 GTPase-activating protein 1 is an enzyme that in humans is encoded by the RAP1GAP gene. This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins.

UniProt: P47736