MMP13 anticorps (AA 110-476)

N° du produit ABIN7870102

Cet anticorps anti-MMP13 Polyclonal Lapin (ABIN7870102) détecte spécifiquement MMP13 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Poisson zèbre (Danio rerio).

Aperçu rapide pour MMP13 anticorps (AA 110-476) (ABIN7870102)

Antigène: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Reactivité: Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP13 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MMP13 anticorps

Épitope: AA 110-476

Fonction: Zebrafish Mmp13a Antibody / Interstitial collagenase

Purification: Antigen affinity chromatography

Immunogène: E. coli-derived zebrafish Mmp13a recombinant protein (amino acids D110-K476) was used as the immunogen for the Zebrafish Mmp13a antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal dilution of the Zebrafish Mmp13a antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Zebrafish Mmp13a antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur MMP13

Antigène: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Autre désignation: Mmp13a

Sujet: Matrix metalloproteinase 13a (Mmp13a) is a member of the matrix metalloproteinase (MMP) family, enzymes that degrade components of the extracellular matrix (ECM). In zebrafish (Danio rerio), Mmp13a plays a pivotal role in tissue remodeling, skeletal development, and regeneration by regulating collagen breakdown and ECM turnover.

Mmp13a is particularly important during craniofacial morphogenesis, bone formation, and fin regeneration, where precise ECM remodeling is essential for cell migration, differentiation, and structural reorganization. Its expression is tightly regulated by signaling pathways such as Wnt, FGF, and TGF-i², and it can be induced in response to injury or developmental cues.

Due to its functional conservation with mammalian MMP13, zebrafish Mmp13a serves as a valuable model for studying osteogenesis, fibrosis, wound healing, and ECM-related diseases, including arthritis and cancer metastasis. Its robust expression during regeneration also makes it a useful biomarker for studies of tissue repair and regenerative biology.

UniProt: F1QCX8