HOXB2 anticorps (AA 114-220)

N° du produit ABIN7870168

Cet anticorps anti-HOXB2 Monoclonal Souris (Clone PCRP-HOXB2-1F2) (ABIN7870168) détecte spécifiquement HOXB2 dans WB, ELISA, IF, IHC (p) et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour HOXB2 anticorps (AA 114-220) (ABIN7870168)

Antigène: HOXB2 (Homeobox B2 (HOXB2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HOXB2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: PCRP-HOXB2-1F2

Détail du produit anti-HOXB2 anticorps

Épitope: AA 114-220

Fonction: HOXB2 Antibody

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 114-220 was used as the immunogen for the HOXB2 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the HOXB2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the HOXB2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur HOXB2

Antigène: HOXB2 (Homeobox B2 (HOXB2))

Autre désignation: HOXB2

Sujet: Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxB1 is critical to hindbrain development and has phenotypic features frequently observed in autism. Analysis of expression and targeted disruption of HoxB1 demonstrates that it is also essential for patterning progenitor cells along the entire DV axis of rhombomere 4 (r4). HoxB1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the Sonic hedgehog and Mash1 signaling pathways. HoxB2 is a homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human adult lung development. HoxB2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, HoxB2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish.

UniProt: P14652