SLFN11 anticorps (AA 114-794)

N° du produit ABIN7870195

Cet anticorps anti-SLFN11 Polyclonal Lapin (ABIN7870195) détecte spécifiquement SLFN11 dans ELISA, WB, FACS et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SLFN11 anticorps (AA 114-794) (ABIN7870195)

Antigène: SLFN11 (Schlafen Family Member 11 (SLFN11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLFN11 est non-conjugé

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SLFN11 anticorps

Épitope: AA 114-794

Fonction: SLFN11 Antibody / Schlafen family member 11

Purification: Affinity purified

Immunogène: An E. coli-derived human protein (amino acids P114-D794) was used as the immunogen for the SLFN11 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the SLFN11 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the SLFN11 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur SLFN11

Antigène: SLFN11 (Schlafen Family Member 11 (SLFN11))

Autre désignation: SLFN11

Sujet: Schlafen family member 11 is a protein that in humans is encoded by the SLFN11 gene. SLFN11 is a nuclear protein that belongs to the Schlafen (SLFN) family of genes involved in cell cycle regulation and growth inhibition. Expression of SLFN11 predicts sensitivity of cancer cell lines to DNA-damaging agents. Evidence suggests that in the presence of DNA-targeted therapies, SLFN11 is recruited to stressed replication forks where it blocks replication leading to cell death. SLFN11 is being explored as a predictive biomarker for response to DNA-targeted therapies.

UniProt: Q7Z7L1