SOX10 anticorps (AA 115-269)

N° du produit ABIN7870208

Cet anticorps Souris Monoclonal détecte spécifiquement SOX10 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SOX10 anticorps (AA 115-269) (ABIN7870208)

Antigène: SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SOX10 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: SOX10-992

Détail du produit anti-SOX10 anticorps

Épitope: AA 115-269

Fonction: SOX10 Antibody

Purification: Protein A/G affinity

Immunogène: A portion of amino acids 115-269 was used as the immunogen for the SOX10 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the SOX10 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SOX10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur SOX10

Antigène: SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

Autre désignation: SOX10

Sujet: SOX-10 is a sensitive marker of melanoma, including conventional, spindled, and desmoplastic subtypes. It is expressed by metastatic melanomas and nodal capsular nevus in sentinel lymph nodes, but not by other lymph node components such as dendritic cells, which usually express S100 protein. Commonly used melanoma markers, such as anti-HMB-45 and anti-Melan-A, are poorly expressed in desmoplastic melanomas while SOX-10 is moderately to strongly expressed in desmoplastic melanomas. SOX-10 is considered as a very reliable marker for recognizing residual desmoplastic melanomas. In normal tissues, it is expressed in Schwann cells, melanocytes, and myoepithelial cells of salivary, bronchial and mammary glands. SOX-10 expression is also observed in mast cells.

UniProt: P56693

Pathways: Chromatin Binding