TJP1 anticorps (AA 1178-1527)

N° du produit ABIN7870254

L’anticorps anti-TJP1 Monoclonal Souris est utilisé pour la détection de TJP1 dans des échantillons de Humain. Il a été validé pour WB, IF, FACS et IHC (p).

Aperçu rapide pour TJP1 anticorps (AA 1178-1527) (ABIN7870254)

Antigène: TJP1 (Tight Junction Protein 1 (TJP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TJP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3E12-

Détail du produit anti-TJP1 anticorps

Épitope: AA 1178-1527

Fonction: TJP1 Antibody / ZO-1

Purification: Affinity purified

Immunogène: A human recombinant protein (amino acids H1178-F1527) was used as the immunogen for the TJP1 antibody.

Isotype: IgG1

Information d'application

Indications d'application: Optimal dilution of the TJP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the TJP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur TJP1

Antigène: TJP1 (Tight Junction Protein 1 (TJP1))

Autre désignation: TJP1

Sujet: Tight junction protein ZO-1 is a protein that in humans is encoded by the TJP1 gene. It is mapped to 15q13.1. This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. It has been found that injected CagA associates with the epithelial tight-junction scaffolding protein TJP1 and the transmembrane protein junctional adhesion molecule, causing an ectopic assembly of tight junction components at sites of bacterial attachment, and altering the composition and function of the apical-junctional complex.

UniProt: Q07157

Pathways: Carbohydrate Homeostasis, Cell-Cell Junction Organization