CPT1A anticorps (AA 122-556)
Aperçu rapide pour CPT1A anticorps (AA 122-556) (ABIN7870339)
Antigène
Voir toutes CPT1A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 122-556
-
Fonction
- CPT1-L Antibody / CPT1A
-
Purification
- Antigen affinity purified
-
Immunogène
- Recombinant human protein (amino acids M122-K556) was used as the immunogen for the CPT1-L antibody.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal dilution of the CPT1-L antibody should be determined by the researcher.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- After reconstitution, the CPT1-L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
-
Autre désignation
- CPT1-L
-
Sujet
- The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
-
UniProt
- P50416
-
Pathways
- AMPK Signaling, Regulation of Lipid Metabolism by PPARalpha, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
Antigène
-