Recombinant MUC16 anticorps (AA 12201-12300)

N° du produit ABIN7870341

L’anticorps anti-MUC16 Monoclonal Lapin est utilisé pour la détection de MUC16 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant MUC16 anticorps (AA 12201-12300) (ABIN7870341)

Antigène: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC16 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: OCA125-4505R

Détail du produit anti-MUC16 anticorps

Épitope: AA 12201-12300

Fonction: Recombinant MUC16 Antibody / CA125 (azide and preservative free)

Purification: Protein A affinity chromatography

Immunogène: A portion of amino acids 12201-12300 from the human protein was used as the immunogen for the recombinant MUC16 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the recombinant MUC16 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant MUC16 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur MUC16

Antigène: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Autre désignation: MUC16

Sujet: CA125 also known as mucin 16, is a member of the mucin family glycoproteins. CA125 is a component of the ocular surface (including the cornea and conjunctiva), the respiratory tract and the female reproductive tract epithelia. Since CA125 is highly glycosylated it creates a hydrophilic environment that acts as a lubricating barrier against foreign particles and infectious agents on the apical membrane of epithelial cells. CA125 reacts with both normal tissues and neoplasms of fallopian tube, endometrium, endocervix and mesothelioma. It does not react with colon cancer. Normal tissues such as breast, liver, skin, kidney and spleen are also negative. Studies have shown that CA125 reacts with approximately 80 % of epithelial ovarian neoplasms of serous, endometrioid, clear cell and undifferentiated types. No reactivity has been shown for mucinous ovarian tumors or in germ cell or hematopoietic tumors. This antibody is a useful aid for classification of a variety of tumors, such as some adenocarcinomas of the colon, breast carcinomas, malignant mesothelioma, uterine adenomatoid tumor, lung bronchoalveolar carcinoma, and ovarian endometrioid and serous carcinomas.

UniProt: Q8WXI7