RNF20 anticorps (AA 123-389)

N° du produit ABIN7870352

Cet anticorps Souris Monoclonal détecte spécifiquement RNF20 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RNF20 anticorps (AA 123-389) (ABIN7870352)

Antigène: RNF20 (Ring Finger Protein 20 (RNF20))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RNF20 est non-conjugé

Application: Western Blotting (WB)

Clone: 3C6E2

Détail du produit anti-RNF20 anticorps

Épitope: AA 123-389

Fonction: RNF20 Antibody / BRE1A

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids E123-S389) was used as the immunogen for the RNF20 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the RNF20 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the RNF20 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur RNF20

Antigène: RNF20 (Ring Finger Protein 20 (RNF20))

Autre désignation: RNF20

Sujet: E3 ubiquitin-protein ligase BRE1A is an enzyme that in humans is encoded by the RNF20 gene. The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS).

UniProt: Q5VTR2