AMOTL2
Reactivité: Humain
WB, IHC, IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
The stated application concentrations are suggested starting points. Titration of the AMOTL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the AMOTL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Antigène
AMOTL2
(Angiomotin Like 2 (AMOTL2))
Autre désignation
AMOTL2
Sujet
AMOTL2 is a member of the angiomotin family of proteins, which are involved in the development and maintenance of blood vessels. It functions as a scaffold protein that helps to organize signaling pathways involved in cell growth and movement. Studies have shown that AMOTL2 is essential for normal development and function of multiple tissues and organs, including the heart, lungs, and kidneys. One of the most intriguing aspects of AMOTL2 is its potential role in cancer progression. Research has shown that dysregulation of AMOTL2 expression is associated with various types of cancer, including breast, lung, and prostate cancer. In some cases, AMOTL2 acts as a tumor suppressor, inhibiting cancer cell growth and metastasis. In other cases, it can promote tumor progression by enhancing angiogenesis and invasiveness.