P-Cadherin anticorps (AA 126-336)

N° du produit ABIN7870395

L’anticorps anti-P-Cadherin Monoclonal Souris est utilisé pour la détection de P-Cadherin dans des échantillons de Humain. Il a été validé pour WB et IF.

Aperçu rapide pour P-Cadherin anticorps (AA 126-336) (ABIN7870395)

Antigène: P-Cadherin (CDH3)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp P-Cadherin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 3C9

Détail du produit anti-P-Cadherin anticorps

Épitope: AA 126-336

Fonction: CDH3 Antibody / P-Cadherin

Purification: Affinity purified

Immunogène: Recombinant human protein (amino acids Q126-H336) was used as the immunogen for the CDH3 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the CDH3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the CDH3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur P-Cadherin

Antigène: P-Cadherin (CDH3)

Autre désignation: CDH3

Sujet: Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

UniProt: P22223