Claudin 6 anticorps (AA 130-159)

N° du produit ABIN7870491

L’anticorps anti-Claudin 6 Polyclonal Lapin est utilisé pour la détection de Claudin 6 dans des échantillons de Souris. Il a été validé pour WB.

Aperçu rapide pour Claudin 6 anticorps (AA 130-159) (ABIN7870491)

Antigène: Claudin 6 (CLDN6)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Claudin 6 anticorps

Épitope: AA 130-159

Fonction: Claudin 6 Antibody / CLDN6

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 130-159 from the human protein was used as the immunogen for the Claudin 6 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Claudin 6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Claudin 6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Claudin 6

Antigène: Claudin 6 (CLDN6)

Autre désignation: Claudin 6

Sujet: Claudin 6 is a protein that in humans is encoded by the CLDN6 gene. It belongs to the group of claudins. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

UniProt: Q99808

Pathways: Hepatitis C