PCDHGA2 anticorps (AA 132-444)

N° du produit ABIN7870515

L’anticorps anti-PCDHGA2 Polyclonal Lapin est utilisé pour la détection de PCDHGA2 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour PCDHGA2 anticorps (AA 132-444) (ABIN7870515)

Antigène: PCDHGA2 (Protocadherin gamma Subfamily A, 2 (PCDHGA2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHGA2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PCDHGA2 anticorps

Épitope: AA 132-444

Fonction: PCDHGA2 Antibody / Protocadherin gamma A2

Purification: Antigen affinity chromatography

Immunogène: An E.coli-derived human recombinant protein (amino acids R132-D444) was used as the immunogen for the PCDHGA2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PCDHGA2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PCDHGA2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PCDHGA2

Antigène: PCDHGA2 (Protocadherin gamma Subfamily A, 2 (PCDHGA2))

Autre désignation: PCDHGA2

Sujet: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

UniProt: Q9Y5H1