ETS1 anticorps (AA 137-230)
Aperçu rapide pour ETS1 anticorps (AA 137-230) (ABIN7870571)
Antigène
Voir toutes ETS1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 137-230
-
Fonction
- ETS1 Antibody
-
Purification
- Protein G affinity chromatography
-
Immunogène
- A recombinant human partial protein (amino acids 137-230) was used as the immunogen for the ETS1 antibody.
-
Isotype
- IgG2b, kappa
-
-
-
-
Indications d'application
- Optimal dilution of the ETS1 antibody should be determined by the researcher.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.2 mg/mL
-
Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store the ETS1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))
-
Autre désignation
- ETS1
-
Sujet
- ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator.The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells.ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes.
-
UniProt
- P14921
Antigène
-