Cet anticorps Lapin Polyclonal détecte spécifiquement LONP1 dans WB, ELISA, IF, IHC (p), IP et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.
LONP1
Reactivité: Humain, Souris, Rat
WB, IF (cc), IF (p)
Hôte: Lapin
Polyclonal
AbBy Fluor® 488
Indications d'application
Optimal dilution of the LONP1 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock
4 °C,-20 °C
Stockage commentaire
After reconstitution, the LONP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Antigène
LONP1
(Lon Peptidase 1, Mitochondrial (LONP1))
Autre désignation
LONP1
Sujet
Lon protease homolog, mitochondrial is an enzyme that in humans is encoded by the LONP1gene. It is mapped to 19p13.3. This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia.