PIK3C3 anticorps (AA 14-39)

N° du produit ABIN7870632

L’anticorps anti-PIK3C3 Polyclonal Lapin est utilisé pour la détection de PIK3C3 dans des échantillons de Humain. Il a été validé pour WB, IF et IHC (p).

Aperçu rapide pour PIK3C3 anticorps (AA 14-39) (ABIN7870632)

Antigène: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3C3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PIK3C3 anticorps

Épitope: AA 14-39

Fonction: PI3KC3 Antibody

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 14-39 from the human protein was used as the immunogen for the PI3KC3 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the PI3KC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the PI3KC3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur PIK3C3

Antigène: PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

Autre désignation: PI3KC3

Sujet: Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). The regulation of the Beclin 1-PI3KC3 complex lipid kinase activity is a critical element in the autophagy signaling pathway.

UniProt: Q8NEB9

Pathways: AMPK Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Toll-Like Receptors Cascades, Autophagy