PRDM8 anticorps (AA 14-405)

N° du produit ABIN7870635

L’anticorps anti-PRDM8 Polyclonal Lapin est utilisé pour la détection de PRDM8 dans des échantillons de Humain. Il a été validé pour WB, ELISA, IF et FACS.

Aperçu rapide pour PRDM8 anticorps (AA 14-405) (ABIN7870635)

Antigène: PRDM8 (PR Domain Containing 8 (PRDM8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRDM8 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-PRDM8 anticorps

Épitope: AA 14-405

Fonction: PRDM8 Antibody / PR domain zinc finger protein 8

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids D14-D405) was used as the immunogen for the PRDM8 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PRDM8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the PRDM8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur PRDM8

Antigène: PRDM8 (PR Domain Containing 8 (PRDM8))

Autre désignation: PRDM8

Sujet: This gene encodes a protein that belongs to a conserved family of histone methyltransferases that predominantly act as negative regulators of transcription. The encoded protein contains an N-terminal Su(var)3-9, Enhancer-of-zeste, and Trithorax (SET) domain and a double zinc-finger domain. Knockout of this gene in mouse results in mistargeting by neurons of the dorsal telencephalon, abnormal itch-like behavior, and impaired differentiation of rod bipolar cells. In humans, the protein has been shown to interact with the phosphatase laforin and the ubiquitin ligase malin, which regulate glycogen construction in the cytoplasm. Alternative splicing results in multiple transcript variants.

UniProt: Q9NQV8