HSD17B10 anticorps (AA 14-48)

N° du produit ABIN7870643

Cet anticorps Lapin Polyclonal détecte spécifiquement HSD17B10 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour HSD17B10 anticorps (AA 14-48) (ABIN7870643)

Antigène: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD17B10 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HSD17B10 anticorps

Épitope: AA 14-48

Fonction: ERAB Antibody / HSD17B10 (N-Terminal Region)

Purification: Antigen affinity

Immunogène: A portion of amino acids 14-48 from human ERAB was used as the immunogen for the ERAB antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the ERAB antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ERAB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur HSD17B10

Antigène: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Autre désignation: ERAB

Sujet: ERAB / HSD17B10 functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD). [UniProt]

UniProt: Q99714