TIMM8A/DDP anticorps (AA 14-97)

N° du produit ABIN7870659

L’anticorps anti-TIMM8A/DDP Polyclonal Lapin est utilisé pour la détection de TIMM8A/DDP dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour ELISA, WB, IHC (p), IF et FACS.

Aperçu rapide pour TIMM8A/DDP anticorps (AA 14-97) (ABIN7870659)

Antigène: TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMM8A/DDP est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-TIMM8A/DDP anticorps

Épitope: AA 14-97

Fonction: TIMM8A Antibody

Purification: Affinity purified

Immunogène: A human recombinant partial protein (amino acids A14-D97) was used as the immunogen for the TIMM8A antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the TIMM8A antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the TIMM8A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur TIMM8A/DDP

Antigène: TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))

Autre désignation: TIMM8A

Sujet: Mitochondrial import inner membrane translocase subunit Tim8 A, also known as Deafness-dystonia peptide or protein is an enzyme that in humans is encoded by the TIMM8A gene. This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome, an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

UniProt: O60220