APCS anticorps (AA 143-223)

N° du produit ABIN7870697

Cet anticorps Souris Monoclonal détecte spécifiquement APCS dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour APCS anticorps (AA 143-223) (ABIN7870697)

Antigène: APCS (Amyloid P Component, Serum (APCS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp APCS est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: APCS-3240

Détail du produit anti-APCS anticorps

Épitope: AA 143-223

Fonction: Serum Amyloid P Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 143-223) was used as the immunogen for the Serum Amyloid P antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Serum Amyloid P antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Serum Amyloid P antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur APCS

Antigène: APCS (Amyloid P Component, Serum (APCS))

Autre désignation: Serum Amyloid P

Sujet: Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins, which has a characteristic pentameric organization and calciumdependent ligand binding. Secreted by liver epithelial cells, SAP is found in serum and urine. Although the function of SAP has not been clearly established, it has been shown to interact with DNA and histones and is thought to play a role in scavenging nuclear material released from damaged circulating cells. Also designated PTX2, SAP is a precursor of the protein amyloid P component (AP), which is universally associated with the amyloid deposits in all forms of amyloidoses, including Alzheimer s disease. SAP is a decamer of ten identical, noncovalently linked subunits, each of which may be post-translationally modified by glycosylation.

UniProt: P02743