APCS anticorps (AA 143-223)

N° du produit ABIN7870698

L’anticorps anti-APCS Monoclonal Souris est utilisé pour la détection de APCS dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour APCS anticorps (AA 143-223) (ABIN7870698)

Antigène: APCS (Amyloid P Component, Serum (APCS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp APCS est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: APCS-3240

Détail du produit anti-APCS anticorps

Épitope: AA 143-223

Fonction: Serum Amyloid P Antibody

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein (amino acids 143-223) was used as the immunogen for the Serum Amyloid P antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the Serum Amyloid P antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Serum Amyloid P antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur APCS

Antigène: APCS (Amyloid P Component, Serum (APCS))

Autre désignation: Serum Amyloid P

Sujet: Serum amyloid P (SAP) is a glycoprotein belonging to the pentraxin family of proteins, which has a characteristic pentameric organization and calciumdependent ligand binding. Secreted by liver epithelial cells, SAP is found in serum and urine. Although the function of SAP has not been clearly established, it has been shown to interact with DNA and histones and is thought to play a role in scavenging nuclear material released from damaged circulating cells. Also designated PTX2, SAP is a precursor of the protein amyloid P component (AP), which is universally associated with the amyloid deposits in all forms of amyloidoses, including Alzheimer s disease. SAP is a decamer of ten identical, noncovalently linked subunits, each of which may be post-translationally modified by glycosylation.

UniProt: P02743