L’anticorps anti-WFDC1 Polyclonal Lapin est utilisé pour la détection de WFDC1 dans des échantillons de Humain. Il a été validé pour WB, FACS et IHC (p).
The stated application concentrations are suggested starting points. Titration of the WFDC1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the WFDC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Antigène
WFDC1
(WAP Four-Disulfide Core Domain 1 (WFDC1))
Autre désignation
WFDC1
Sujet
This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81 % amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.