PNPLA6 anticorps (AA 15-1296)
Aperçu rapide pour PNPLA6 anticorps (AA 15-1296) (ABIN7870780)
Antigène
Voir toutes PNPLA6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 15-1296
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Fonction
- PNPLA6 Antibody / NTE
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Purification
- Antigen affinity purified
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Immunogène
- E. coli-derived recombinant human protein (amino acids H15-E1296) was used as the immunogen for the PNPLA6 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the PNPLA6 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the PNPLA6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))
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Autre désignation
- PNPLA6
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Sujet
- Neuropathy target esterase (NTE), also known as patatin-like phospholipase domain-containing protein 6 (PNPLA6), is an esterase enzyme that in humans is encoded by the PNPLA6 gene. This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q8IY17
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Pathways
- Ribonucleoside Biosynthetic Process
Antigène
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