Transgelin anticorps (AA 15-170)

N° du produit ABIN7870782

L’anticorps anti-Transgelin Polyclonal Lapin est utilisé pour la détection de Transgelin dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, FACS, IHC (p) et IF.

Aperçu rapide pour Transgelin anticorps (AA 15-170) (ABIN7870782)

Antigène: Transgelin (TAGLN)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transgelin est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-Transgelin anticorps

Épitope: AA 15-170

Fonction: TAGLN Antibody / Transgelin / SM22 alpha

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids Q15-E170) was used at the immunogen for the TAGLN antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the TAGLN antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the TAGLN antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Transgelin

Antigène: Transgelin (TAGLN)

Autre désignation: TAGLN

Sujet: Transgelin, also known as SM22 alpha, is a protein that in humans is encoded by the TAGLN gene. This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization.

UniProt: Q01995