Merlin anticorps (AA 15-565)

N° du produit ABIN7870799

Cet anticorps Lapin Polyclonal détecte spécifiquement Merlin dans WB, ELISA, IF, IHC (p) et FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Merlin anticorps (AA 15-565) (ABIN7870799)

Antigène: Merlin (NF2) (Neurofibromin 2 (NF2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Merlin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Détail du produit anti-Merlin anticorps

Épitope: AA 15-565

Fonction: Merlin Antibody / NF2

Purification: Affinity purified

Immunogène: A human recombinant protein (amino acids K15-N565) was used as the immunogen for the Merlin antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Merlin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Merlin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Merlin

Antigène: Merlin (NF2) (Neurofibromin 2 (NF2))

Autre désignation: Merlin

Sujet: Human merlin is coded by the gene NF2 on chromosome 22. It is mapped to 22q12.2. This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development, in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.

UniProt: P35240

Pathways: Cell-Cell Junction Organization