Paired Box 3 anticorps (AA 150-350)

N° du produit ABIN7870938

L’anticorps anti-Paired Box 3 Monoclonal Souris est utilisé pour la détection de Paired Box 3 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Paired Box 3 anticorps (AA 150-350) (ABIN7870938)

Antigène: Paired Box 3 (PAX3)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Paired Box 3 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: PAX3-8424

Détail du produit anti-Paired Box 3 anticorps

Épitope: AA 150-350

Fonction: Paired box 3 Antibody / PAX3 (azide and preservative free)

Purification: Protein G affinity

Immunogène: A portion of amino acids 150-350 from human PAX3 protein was used as the immunogen for the Paired box 3 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Paired box 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the Paired box 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Paired Box 3

Antigène: Paired Box 3 (PAX3)

Autre désignation: Paired box 3

Sujet: Pax genes contain paired domains that share strong homology to genes in Drosophila which are involved in programming early development. The product of the PAX3 gene is a DNA-binding protein expressed during early neurogenesis. Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis, Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain, midbrain and diencephalon. In 10-12 day embryos, expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia, the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes, encoding transcription factors, are responsible for Waardenburg syndrome II (WSII) and WSI/WSIII, respectively.

UniProt: P23760

Pathways: Sensory Perception of Sound, Tube Formation